Diabetes Newsletter
Spring 2012
Both type 1 and type 2 diabetes can be treated and managed with healthy eating, physical activity, and taking medications such as insulin to control blood glucose levels. Yale is also conducting research to develop new treatments as well as prevent diabetes in those at risk.
Why Research Matters
In 1979 Dr. Robert Sherwin and Dr. William Tamborlane developed the insulin pump to treat type 1 diabetes. Today it’s used by more than 350,000 patients. Without volunteers like the children and their families who were willing to participate in clinical research, this groundbreaking discovery would not have been possible.
Tips for Controlling Diabetes
When you take care of your diabetes, you’ll feel better. You’ll reduce your risk for problems with your kidneys, eyes, nerves, feet and legs, and teeth. You’ll also lower your risk for a heart attack or a stroke. Your doctor may prescribe medication, but you can also take care of your diabetes by being physically active and following a healthy meal plan.
Research to Treat and Prevent Type 1 Diabetes
When Hannah Rosenfield was diagnosed with Type 1 diabetes at age 10, her mother Amy immediately looked beyond the standard treatment for something that might benefit her daughter long term.
Understanding the Root of Type 2 Diabetes
Dr. Gerald Shulman is working to uncover what happens in cells that leads to insulin resistance, which is at the core of type 2 diabetes. His research is pointing to new drug targets as well as exercise and dietary strategies that may lead to the reversal of insulin resistance and the prevention of type 2 diabetes.
Upcoming Diabetes Trial A study comparing the effectiveness of three different classes of medications in patients already taking Metformin for Type 2 diabetes. Please check back in November for details. | ||
Diabetes & Related Research Trials
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| Changing Lifestyles for Better Health Disease/Condition: Type 2 Diabetes Mellitus Principal Investigator: Tamborlane, William V |
| Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes. Disease/Condition: Hypo-unawareness | Type 1 Diabetes. Principal Investigator: Robert Sherwin, MD |
| Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes. Disease/Condition: Type 1 Diabetes Principal Investigator: Robert Sherwin, MD |
| Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia Disease/Condition: Hypoglycemia Principal Investigator: Robert Sherwin, MD |
| Insulin Resistance Intervention After Stroke Trial Disease/Condition: Diabetes | Myocardial Infarction | Stroke Principal Investigator: Kernan, Walter Newberry |
| Internet Treatment for Weight Loss in Primary Care Disease/Condition: Obese | Overweight Principal Investigator: Rachel Barnes, Ph.D. |
| Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers Disease/Condition: Obesity | Overweight | Smoking Cessation Principal Investigator: Marney A White, PhD, MS |
| Investigation Into Effects Upon Counterregulatory Responses to Hypoglycemia During Intensive Treatment of T1DM Disease/Condition: Hypoglycemia | Type 1 Diabetes Principal Investigator: Sherwin, Robert Stanley |
| Natural History Study of the Development of Type 1 Diabetes Disease/Condition: Diabetes Mellitus, Type 1 Principal Investigator: Herold, Kevan |
| Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus Disease/Condition: Diabetes Mellitus, Type 1 Principal Investigator: Herold, Kevan |
| Prevalence of Carbohydrate Intolerance in Lean and Obese Children Disease/Condition: Acanthosis Nigricans | Diabetes | Glucose Intolerance | Obesity Principal Investigator: Caprio, Sonia |
| Stress Management Among Latinos With Type 2 Diabetes Disease/Condition: Diabetes Mellitus, Type 2 Principal Investigator: Rafael Pérez-Escamilla, Ph.D. |
| Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth Disease/Condition: Beta-cell Function | Childhood Obesity | Impaired Glucose Tolerance | Metabolic Syndrome | Pre-diabetes Principal Investigator: Caprio, Sonia |
| T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs Disease/Condition: Type 1 Diabetes Mellitus Principal Investigator: Kevan Herold |
| Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk" Disease/Condition: Autoantibody Positive | High Risk | Impaired Glucose Tolerance | Non-diabetic Relatives at Risk for Type 1 Diabetes Principal Investigator: Kevan Herold, MD |
| The Testosterone Trial in Older Men Disease/Condition: Andropause Principal Investigator: Thomas Gill, M.D. |
| TODAY Genetics Study Disease/Condition: Type 2 Diabetes Principal Investigator: Sonia Caprio, MD |
| Treatment of Binge Eating in Obese Patients in Primary Care Disease/Condition: Binge Eating | Obesity Principal Investigator: Grilo, Carlos M |
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